Quite difficult looking words….aren’t they? Let’s start with ‘Ambi’ , which is common between the two words – Ambi is not a word but a root which means ‘both’ or ‘both sides’ . ‘Ambidextrous’ is someone who is skillful in using both the right and left hand equally well. Similarly, ‘Ambisinister’ is someone who is clumsy or unskillful with both the hands.